Recombinant MLH1 anticorps (AA 450-500)

N° du produit ABIN7455102

Cet anticorps Lapin Monoclonal détecte spécifiquement MLH1 dans WB, ICC, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant MLH1 anticorps (AA 450-500) (ABIN7455102)

Antigène: MLH1 (MutL Homolog 1 (MLH1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MLH1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BLR112H

Détail du produit anti-MLH1 anticorps

Épitope: AA 450-500

Fonction: Rabbit anti-MLH1 Recombinant Monoclonal Antibody [BLR112H]

Immunogène: between AA 450 and 500

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 6 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MLH1

Antigène: MLH1 (MutL Homolog 1 (MLH1))

Autre désignation: MLH1

Sujet: Background: MLH1 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MLH1 can heterodimerize with DNA mismatch repair protein MLH3 and with mismatch repair endonuclease PMS2. [taken from NCBI Entrez Gene (Gene ID: 4292)].

ID gène: 4292

NCBI Accession: NP_000240

UniProt: P40692

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response