Progesterone Receptor anticorps

N° du produit ABIN7455133

L’anticorps Souris Monoclonal anti-Progesterone Receptor a été validé pour WB, IP, ICC, FACS et IHC (fp). Il convient pour détecter Progesterone Receptor dans des échantillons de Humain.

Aperçu rapide pour Progesterone Receptor anticorps (ABIN7455133)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: 188

Détail du produit anti-Progesterone Receptor anticorps

Fonction: Mouse anti-Progesterone Receptor Monoclonal Antibody [188]

Immunogène: recombinant human Progesterone Receptor

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 6 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: Progesterone Receptor

Sujet: Background: The progesterone receptor (PR) is a member of the steroid receptor superfamily that binds progesterone and is critical to all aspects of reproductive development and the establishment and maintenance of pregnancy. When bound by progesterone, PR enters the nucleus to function in gene-specific transcriptional activation. Progesterone receptor expression is regulated by estrogen. Recent studies have found that the status of the progesterone receptor in breast tumors may be an indicator of how tumors will respond to tamoxifen treatment.

ID gène: 5241

NCBI Accession: NP_000917

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration