Recombinant MSH6 anticorps (AA 1310-1360)

N° du produit ABIN7455152

Cet anticorps anti-MSH6 est un anticorps Lapin Monoclonal détectant MSH6 dans WB, IHC (fp), FACS, ICC et IP. Adapté pour Humain.

Aperçu rapide pour Recombinant MSH6 anticorps (AA 1310-1360) (ABIN7455152)

Antigène: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MSH6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR117H

Détail du produit anti-MSH6 anticorps

Épitope: AA 1310-1360

Fonction: Rabbit anti-MSH6 Recombinant Monoclonal Antibody [BLR117H]

Immunogène: between AA 1310 and 1360 (C-term)

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MSH6

Antigène: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Autre désignation: MSH6

Sujet: Background: MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma.

ID gène: 2956

NCBI Accession: NP_000170

UniProt: P52701

Pathways: Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response