KIF14 anticorps (C-Term)

N° du produit ABIN7455214

L’anticorps Lapin Polyclonal anti-KIF14 a été validé pour WB, IP, IF/ICC et IHC (fp). Il convient pour détecter KIF14 dans des échantillons de Humain.

Aperçu rapide pour KIF14 anticorps (C-Term) (ABIN7455214)

Antigène: KIF14 (Kinesin Family Member 14 (KIF14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF14 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-KIF14 anticorps

Épitope: C-Term

Fonction: Rabbit anti-KIF14 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1600 and C-term

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:200 - 1:1,000. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIF14

Antigène: KIF14 (Kinesin Family Member 14 (KIF14))

Autre désignation: KIF14

Sujet: Background: The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF14 silencing experiments suggest that KIF14 plays a multi-functional role in mitosis and cytokinesis. KIF14 has also been identified as a candidate oncogene whose overexpression may lead to genomic instability and act as a reporter of poor-prognosis in breast cancer.

ID gène: 9928

NCBI Accession: NP_055690

UniProt: Q15058