IL-5 anticorps
Aperçu rapide pour IL-5 anticorps (ABIN7490567)
Antigène
Voir toutes IL-5 (IL5) AnticorpsFragment
Reactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Rabbit/Human Fc chimeric IgG1
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Autre désignation
- IL5
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Sujet
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IL-5,TRF,Interleukin-5,EDF,
Description: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. -
UniProt
- P05113
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Pathways
- Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Antigène
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