CCR2 anticorps
Aperçu rapide pour CCR2 anticorps (ABIN7490750)
Antigène
Voir toutes CCR2 AnticorpsFragment
Reactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Rabbit/Human Fc chimeric IgG1
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Autre désignation
- CCR2
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Sujet
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CC-CKR-2, MCP-1-R, CD192,
Description: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. -
UniProt
- P41597
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Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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