CCR1 anticorps
Aperçu rapide pour CCR1 anticorps (ABIN7490774)
Antigène
Voir toutes CCR1 AnticorpsFragment
Reactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Rabbit/Human Fc chimeric IgG1
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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Autre désignation
- CCR1
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Sujet
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CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1,
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] -
UniProt
- P32246
Antigène
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