DDR1 anticorps
Aperçu rapide pour DDR1 anticorps (ABIN7490834)
Antigène
Voir toutes DDR1 AnticorpsFragment
Reactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Rabbit/Human Fc chimeric IgG1
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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Autre désignation
- DDR1
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Sujet
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CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, MCK-10, HGK2, CD167a,
Description: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] -
UniProt
- Q08345
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Pathways
- Signalisation RTK, Smooth Muscle Cell Migration
Antigène
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