IL-5 anticorps (APC)

N° du produit ABIN7456564

L’anticorps Rat Monoclonal anti-IL-5 a été validé pour ICFC. Il convient pour détecter IL-5 dans des échantillons de Humain.

Aperçu rapide pour IL-5 anticorps (APC) (ABIN7456564)

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-5 est conjugé à/à la APC

Application: Intracellular Flow Cytometry (ICFC)

Clone: TRFK5

Détail du produit anti-IL-5 anticorps (APC)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: APC Rat IgG1, κ Isotype Control (ABIN7469823)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur IL-5

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Autre désignation: IL-5

Sujet: Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF,IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

ID gène: 3567, 16191

UniProt: P05113, P04401

Pathways: Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour