CD8 alpha anticorps (Biotin)

N° du produit ABIN7456670

Cet anticorps anti-CD8 alpha est un anticorps Rat Monoclonal détectant CD8 alpha dans FACS. Adapté pour Souris.

Aperçu rapide pour CD8 alpha anticorps (Biotin) (ABIN7456670)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: 53-6-7

Détail du produit anti-CD8 alpha anticorps (Biotin)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Commentaires:

Matching Isotype Control: Biotin Rat IgG2a, κ Isotype Control (ABIN7469838)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8a

Sujet: T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL,CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

ID gène: 12525

UniProt: P01731

Pathways: TCR Signaling