CCR7 anticorps (FITC)

N° du produit ABIN7456842

Cet anticorps Souris Monoclonal détecte spécifiquement CCR7 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CCR7 anticorps (FITC) (ABIN7456842)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR7 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: G043H7

Détail du produit anti-CCR7 anticorps (FITC)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: FITC Mouse IgG2a, κ Isotype Control (ABIN7469777)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CD197

Sujet: CMKBR7, EBI1, EVI1,CCR-7,CDw197,CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. Product Details

ID gène: 1236

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process