IL-21 anticorps (PE)

N° du produit ABIN7457148

Cet anticorps Souris Monoclonal détecte spécifiquement IL-21 dans ICFC. Il présente une réactivité envers Humain.

Aperçu rapide pour IL-21 anticorps (PE) (ABIN7457148)

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-21 est conjugé à/à la PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: 3A3-N2

Détail du produit anti-IL-21 anticorps (PE)

Isotype: IgG1, kappa

Information d'application

Indications d'application: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: PE Mouse IgG1, κ Isotype Control (ABIN7469761)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur IL-21

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: IL-21

Sujet: Interleukin-21,IL-21,Za11,Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

ID gène: 59067

UniProt: Q9HBE4

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response