Fc gamma RII (CD32) anticorps (PE-Cy7)

N° du produit ABIN7457520

Cet anticorps Souris Monoclonal détecte spécifiquement dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour Fc gamma RII (CD32) anticorps (PE-Cy7) (ABIN7457520)

Antigène: Fc gamma RII (CD32)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: PE-Cy7

Application: Flow Cytometry (FACS)

Clone: IV-3

Détail du produit

Isotype: IgG2b, kappa

Information d'application

Indications d'application: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: PE/Cyanine7 Mouse IgG2b, κ Isotype Control (ABIN7469798)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détail du antigène

Antigène: Fc gamma RII (CD32)

Autre désignation: CD32

Sujet: Low affinity immunoglobulin gamma Fc region receptor II-b,FCGR2B,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b,Fc-gamma-RIIb,FcRII-b,CD32,FCG2, IGFR2,CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

ID gène: 2212

UniProt: P31994