IL-5 anticorps

N° du produit ABIN7457979

Cet anticorps Rat Monoclonal détecte spécifiquement IL-5 dans Neut, ICFC et Dep. Il présente une réactivité envers Humain.

Aperçu rapide pour IL-5 anticorps (ABIN7457979)

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-5 est non-conjugé

Application: Neutralization (Neut), Intracellular Flow Cytometry (ICFC), Depletion (Dep)

Clone: TRFK5

Détail du produit anti-IL-5 anticorps

Purification: Purified

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Matching Isotype Control: AF/LE Purified Rat IgG1, κ Isotype Control (ABIN7469818)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur IL-5

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Autre désignation: IL-5

Sujet: Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF,IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

ID gène: 3567, 16191

UniProt: P05113, P04401

Pathways: Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour