FH anticorps

N° du produit ABIN7464916

L’anticorps Souris Monoclonal anti-FH a été validé pour WB, IF et ICC. Il convient pour détecter FH dans des échantillons de Humain.

Aperçu rapide pour FH anticorps (ABIN7464916)

Antigène: FH (Fumarate Hydratase (FH))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: KO Validated

Clone: GT7612

Détail du produit anti-FH anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Affinity purified by Protein G.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Fumarate hydratase. The exact sequence is proprietary.

Isotype: IgG3

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: rat liver , mouse liver , 293T , A431 , HeLa , HepG2

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur FH

Antigène: FH (Fumarate Hydratase (FH))

Autre désignation: fumarate hydratase

Sujet: Fumarate hydratase , FMRD , HLRCC , LRCC , MCL , MCUL1,The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]

Poids moléculaire: 55 kDa

ID gène: 2271

UniProt: P07954