Emerin anticorps (AA 25-125) (Cy5)

N° du produit ABIN719565

Détail du produit anti-Emerin anticorps (Cy5)

Antigène: Emerin (EMD)

Épitope: AA 25-125

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Emerin est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Emerin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Emerin

Antigène: Emerin (EMD)

Autre désignation: Emerin (EMD Produits)

Synonymes: anticorps fj58f01, anticorps wu:fj58f01, anticorps EMD, anticorps Bocks, anticorps Bocksbeutel, anticorps CG9424, anticorps Dmel\\CG9424, anticorps emerin, anticorps emd, anticorps xemd1, anticorps xemerin2, anticorps xemd2, anticorps xemerin1, anticorps EDMD, anticorps LEMD5, anticorps STA, anticorps AW550900, anticorps Sta, anticorps emerin, anticorps emerin (Emery-Dreifuss muscular dystrophy), anticorps bocksbeutel, anticorps emerin L homeolog, anticorps emerin S homeolog, anticorps EMD, anticorps emd, anticorps bocks, anticorps emd.L, anticorps emd.S, anticorps Emd

Sujet:

Synonyms: EDMD, EMD, EMD_HUMAN, Emerin, Emery Dreuss muscular dystrophy, STA.

Background: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity, Skeletal muscle, heart, colon, testis, ovary and pancreas.

ID gène: 2010