EIF3H anticorps
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- Antigène Voir toutes EIF3H Anticorps
- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp EIF3H est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Affinity purified by Protein G.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human eIF3H / EIF3S3. The exact sequence is proprietary.
- Clone
- GT2712
- Isotype
- IgG1
- Top Product
- Discover our top product EIF3H Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: A431
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, No Preservative
- Agent conservateur
- Without preservative
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
- Autre désignation
- eukaryotic translation initiation factor 3 subunit H (EIF3H Produits)
- Synonymes
- anticorps EIF3S3, anticorps eIF3-gamma, anticorps eIF3-p40, anticorps 1110008A16Rik, anticorps 40kD, anticorps 9430017H16Rik, anticorps EIF3-P40, anticorps EIF3-gamma, anticorps Eif3s3, anticorps eif3s3, anticorps eIF-3p40, anticorps En10, anticorps AO090038000435, anticorps EIF3H, anticorps eIF3h, anticorps BcDNA:GM14618, anticorps CG9124, anticorps Dmel\\CG9124, anticorps eIF-3, anticorps eIF3-S3, anticorps eIf3-p44, anticorps l(2)k09003, anticorps eIF3h-A, anticorps eif3h, anticorps fj02c04, anticorps wu:fj02c04, anticorps zgc:101085, anticorps eIF3h-B, anticorps zgc:123049, anticorps eukaryotic translation initiation factor 3 subunit H, anticorps eukaryotic translation initiation factor 3, subunit H, anticorps eukaryotic translation initiation factor 3 subunit H S homeolog, anticorps eukaryotic translation initiation factor 3 subunit H-like, anticorps Eukaryotic initiation factor 3 p40 subunit, anticorps eukaryotic translation initiation factor 3, subunit H, a, anticorps Eukaryotic translation initiation factor 3 subunit H, anticorps translation initiation factor eIF3h (p40), anticorps eukaryotic translation initiation factor 3, subunit H, b, anticorps EIF3H, anticorps Eif3h, anticorps eif3h, anticorps eif3h.S, anticorps eIF3h, anticorps AOR_1_722074, anticorps PAAG_02837, anticorps VDBG_01433, anticorps MGYG_06658, anticorps LOC100196680, anticorps eIF-3p40, anticorps eif3ha, anticorps eif-3.H, anticorps SPAC821.05, anticorps eif3hb
- Sujet
- Eukaryotic translation initiation factor 3 subunit H , EIF3S3 , eIF3-gamma , eIF3-p40,Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- Poids moléculaire
- 40 kDa
- ID gène
- 8667
- UniProt
- O15372
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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