EIF3H anticorps (C-Term)

N° du produit ABIN1882076

Détail du produit anti-EIF3H anticorps

Antigène: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Épitope: AA 234-263, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3H est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B, C, X

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This EIF3H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the C-terminal region of human EIF3H.

Clone: RB20154

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-EIF3H (ABIN1882076)

Cappuzzo, Varella-Garcia, Rossi, Gajapathy, Valente, Drabkin, Gemmill: "MYC and EIF3H Coamplification significantly improve response and survival of non-small cell lung cancer patients (NSCLC) treated with gefitinib." dans: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 4, Issue 4, pp. 472-8, (2009) (PubMed).

Détails sur EIF3H

Antigène: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Autre désignation: EIF3H (EIF3H Produits)

Synonymes: anticorps EIF3S3, anticorps eIF3-gamma, anticorps eIF3-p40, anticorps 1110008A16Rik, anticorps 40kD, anticorps 9430017H16Rik, anticorps EIF3-P40, anticorps EIF3-gamma, anticorps Eif3s3, anticorps eif3s3, anticorps eIF-3p40, anticorps En10, anticorps AO090038000435, anticorps EIF3H, anticorps eIF3h, anticorps BcDNA:GM14618, anticorps CG9124, anticorps Dmel\\CG9124, anticorps eIF-3, anticorps eIF3-S3, anticorps eIf3-p44, anticorps l(2)k09003, anticorps eIF3h-A, anticorps eif3h, anticorps fj02c04, anticorps wu:fj02c04, anticorps zgc:101085, anticorps eIF3h-B, anticorps zgc:123049, anticorps eukaryotic translation initiation factor 3 subunit H, anticorps eukaryotic translation initiation factor 3, subunit H, anticorps eukaryotic translation initiation factor 3 subunit H S homeolog, anticorps eukaryotic translation initiation factor 3 subunit H-like, anticorps Eukaryotic initiation factor 3 p40 subunit, anticorps eukaryotic translation initiation factor 3, subunit H, a, anticorps Eukaryotic translation initiation factor 3 subunit H, anticorps translation initiation factor eIF3h (p40), anticorps eukaryotic translation initiation factor 3, subunit H, b, anticorps EIF3H, anticorps Eif3h, anticorps eif3h, anticorps eif3h.S, anticorps eIF3h, anticorps AOR_1_722074, anticorps PAAG_02837, anticorps VDBG_01433, anticorps MGYG_06658, anticorps LOC100196680, anticorps eIF-3p40, anticorps eif3ha, anticorps eif-3.H, anticorps SPAC821.05, anticorps eif3hb

Sujet: EIF3H is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Poids moléculaire: 39930

NCBI Accession: NP_003747

UniProt: O15372

Pathways: Ribonucleoprotein Complex Subunit Organization