C4A anticorps (N-Term)

N° du produit ABIN7466047

L’anticorps Lapin Polyclonal anti-C4A a été validé pour WB et IHC (p). Il convient pour détecter C4A dans des échantillons de Humain.

Aperçu rapide pour C4A anticorps (N-Term) (ABIN7466047)

Antigène: C4A (C4a) (Complement Fragment C4a (C4a))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C4A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-C4A anticorps

Épitope: N-Term

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human C4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.52 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur C4A

Antigène: C4A (C4a) (Complement Fragment C4a (C4a))

Autre désignation: complement component 4A (Rodgers blood group)

Sujet: C4 antibody , C4A2 antibody , C4A3 antibody , C4A4 antibody , C4A6 antibody , C4S antibody , CO4 antibody , CPAMD2 antibody , MGC164979 antibody , RG antibody , C4A antibody , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody , C4A anaphylatoxin antibody , acidic C4 antibody , acidic complement C4 antibody , Rodgers form of C4 antibody , complement C4-A antibody , complement component 4A (Rodgers blood group) antibody,This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq]

Poids moléculaire: 193 kDa

ID gène: 720

Pathways: Système du Complément