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Progesterone Receptor anticorps (AA 1-101)

Cet anticorps anti-Progesterone Receptor est un anticorps Souris Monoclonal détectant Progesterone Receptor dans WB. Adapté pour Humain.
N° du produit ABIN7466678

Aperçu rapide pour Progesterone Receptor anticorps (AA 1-101) (ABIN7466678)

Antigène

Voir toutes Progesterone Receptor (PGR) Anticorps
Progesterone Receptor (PGR)

Reactivité

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Humain

Hôte

  • 154
  • 70
  • 1
Souris

Clonalité

  • 147
  • 77
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Monoclonal

Conjugué

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Cet anticorp Progesterone Receptor est non-conjugé

Application

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Western Blotting (WB)

Clone

4D8
  • Épitope

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    AA 1-101

    Specificité

    This antibody recognizes both Form A (94 kDa) and Form B (120 kDa) of the human progesterone receptor (PgR)

     Réactivité croisée

    Humain

    Purification

    Protein G purified

    Immunogène

    6-His fusion protein containing the region encoding amino acids 1-101 of the human progesterone receptor expressed in E. coli.

    Isotype

    IgG2a
  • Indications d'application

    WB: 1 - 5 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: MCF7 lysate (GTX23871) & recombinant protein

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS pH 7.2, No Preservative

    Agent conservateur

    Without preservative

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Progesterone Receptor (PGR)

    Autre désignation

    progesterone receptor

    Sujet

    Progesterone receptor , NR3C3 , PR,This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

    Poids moléculaire

    99 kDa

    ID gène

    5241

    UniProt

    P06401

    Pathways

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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