ARNT2 anticorps
Aperçu rapide pour ARNT2 anticorps (ABIN7466727)
Antigène
Voir toutes ARNT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Souris
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human ARNT2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Mouse brain
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.47 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))
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Autre désignation
- aryl hydrocarbon receptor nuclear translocator 2
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Sujet
- Aryl hydrocarbon receptor nuclear translocator 2 , WEDAS , bHLHe1,This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq]
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Poids moléculaire
- 79 kDa
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ID gène
- 9915
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UniProt
- Q9HBZ2
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Pathways
- L'effet Warburg
Antigène
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