BBS4 anticorps (N-Term)

N° du produit ABIN7466958

Cet anticorps Lapin Polyclonal détecte spécifiquement BBS4 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour BBS4 anticorps (N-Term) (ABIN7466958)

Antigène: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BBS4 anticorps

Épitope: N-Term

Réactivité croisée: Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human BBS4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Neuro2A , C8D30 , NIH-3T3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.04 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur BBS4

Antigène: BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Autre désignation: Bardet-Biedl syndrome 4

Sujet: Bardet-Biedl syndrome 4,This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.

Poids moléculaire: 58 kDa

ID gène: 585

UniProt: Q96RK4

Pathways: Signalisation Hedgehog, Tube Formation, Maintenance of Protein Location