MADD anticorps

N° du produit ABIN7466967

Cet anticorps Lapin Polyclonal détecte spécifiquement MADD dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour MADD anticorps (ABIN7466967)

Antigène: MADD (MAP-Kinase Activating Death Domain (MADD))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MADD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MADD anticorps

Réactivité croisée: Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse MADD. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Neuro2A , Raw264.7

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.39 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur MADD

Antigène: MADD (MAP-Kinase Activating Death Domain (MADD))

Autre désignation: MAP-kinase activating death domain

Sujet: MAP-kinase activating death domain , 9630059K23Rik , IG20,Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis).

Poids moléculaire: 175 kDa

ID gène: 228355

UniProt: Q80U28

Pathways: Caspase Cascade in Apoptosis