Phospholamban anticorps (pSer16)

N° du produit ABIN7467195

Cet anticorps Lapin Polyclonal détecte spécifiquement Phospholamban dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Phospholamban anticorps (pSer16) (ABIN7467195)

Antigène: Phospholamban (PLN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholamban est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Phospholamban anticorps

Épitope: pSer16

Réactivité croisée: Souris, Lapin

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide surrounding phospho Ser16 of human Phospholamban. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.97 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Phospholamban

Antigène: Phospholamban (PLN)

Autre désignation: phospholamban

Sujet: Phospholamban , CMD1P , CMH18 , PLB,The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]

Poids moléculaire: 6 kDa

ID gène: 5350

UniProt: P26678

Pathways: Negative Regulation of Transporter Activity