GIPR anticorps (N-Term)

N° du produit ABIN7467374

Cet anticorps anti-GIPR est un anticorps Lapin Polyclonal détectant GIPR dans WB. Adapté pour Humain.

Aperçu rapide pour GIPR anticorps (N-Term) (ABIN7467374)

Antigène: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIPR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GIPR anticorps

Épitope: N-Term

Réactivité croisée: Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GIPR. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.53 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GIPR

Antigène: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Autre désignation: gastric inhibitory polypeptide receptor

Sujet: Gastric inhibitory polypeptide receptor , PGQTL2,Gastric inhibitory polypeptide (GIP, MIM 137240), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. It is involved in several other facets of the anabolic response.[supplied by OMIM]

Poids moléculaire: 53 kDa

ID gène: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling