SKA1 anticorps

N° du produit ABIN7467814

L’anticorps anti-SKA1 Polyclonal produit chez le Lapin a été validé pour IHC (p). Il convient pour la détection de SKA1 dans des échantillons provenant de Humain. }

Aperçu rapide pour SKA1 anticorps (ABIN7467814)

Antigène: SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKA1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SKA1 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human SKA1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur SKA1

Antigène: SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))

Autre désignation: spindle and kinetochore associated complex subunit 1

Sujet: Spindle and kinetochore associated complex subunit 1 , C18orf24,Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.

Poids moléculaire: 29 kDa

ID gène: 220134

UniProt: Q96BD8

Pathways: M Phase