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Klotho beta anticorps

KLB Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7467855
  • Antigène Voir toutes Klotho beta (KLB) Anticorps
    Klotho beta (KLB)
    Reactivité
    • 16
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 22
    • 1
    Lapin
    Clonalité
    • 22
    • 1
    Polyclonal
    Conjugué
    • 13
    • 7
    • 2
    • 1
    Cet anticorp Klotho beta est non-conjugé
    Application
    • 18
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human KLB. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product KLB Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    Klotho beta (KLB)
    Autre désignation
    klotho beta (KLB Produits)
    Synonymes
    anticorps KLB, anticorps BKL, anticorps AV071179, anticorps betaKlotho, anticorps Klb-ps1, anticorps RGD1308227, anticorps klotho beta, anticorps KLB, anticorps Klb
    Sujet
    Klotho beta , BKL,Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
    Poids moléculaire
    120 kDa
    ID gène
    152831
    UniProt
    Q86Z14
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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