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ARID1A anticorps (C-Term)

ARID1A Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Souris Monoclonal GT3611 unconjugated
N° du produit ABIN7467969
  • Antigène Voir toutes ARID1A Anticorps
    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
    Épitope
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 33
    • 19
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 2
    Souris
    Clonalité
    • 24
    • 9
    Monoclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp ARID1A est non-conjugé
    Application
    • 12
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris
    Purification
    Affinity purified by Protein G.
    Immunogène
    Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A. The exact sequence is proprietary.
    Clone
    GT3611
    Isotype
    IgG1
    Top Product
    Discover our top product ARID1A Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.61 mg/mL
    Buffer
    PBS, No Preservative
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
    Autre désignation
    AT-rich interaction domain 1A (ARID1A Produits)
    Synonymes
    anticorps B120, anticorps BAF250, anticorps BAF250a, anticorps BM029, anticorps C1orf4, anticorps ELD, anticorps MRD14, anticorps OSA1, anticorps P270, anticorps SMARCF1, anticorps hELD, anticorps hOSA1, anticorps 1110030E03Rik, anticorps Osa1, anticorps Smarcf1, anticorps ARID1A, anticorps wu:fb79b07, anticorps wu:fb95g08, anticorps zgc:171438, anticorps AT-rich interaction domain 1A, anticorps AT rich interactive domain 1A (SWI-like), anticorps AT rich interactive domain 1Aa (SWI-like), anticorps ARID1A, anticorps Arid1a, anticorps arid1a, anticorps arid1aa
    Sujet

    Synonyms: AT-rich interaction domain 1A , B120 , BAF250 , BAF250a , BM029 , C1orf4 , CSS2 , ELD , MRD14 , OSA1 , P270 , SMARCF1 , hELD , hOSA1

    Background: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    Poids moléculaire
    242 kDa
    ID gène
    8289
    UniProt
    O14497
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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