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Calnexin anticorps (C-Term)

Cet anticorps anti-Calnexin est un anticorps Lapin Polyclonal détectant Calnexin dans WB, IF, IP, ICC et IHC (p). Adapté pour Humain.
N° du produit ABIN7468094

Aperçu rapide pour Calnexin anticorps (C-Term) (ABIN7468094)

Antigène

Voir toutes Calnexin (CANX) Anticorps
Calnexin (CANX)

Reactivité

  • 135
  • 79
  • 75
  • 47
  • 31
  • 29
  • 29
  • 27
  • 27
  • 23
  • 23
  • 22
  • 19
  • 19
  • 18
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 122
  • 39
  • 7
Lapin

Clonalité

  • 119
  • 50
Polyclonal

Conjugué

  • 77
  • 9
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Calnexin est non-conjugé

Application

  • 138
  • 96
  • 60
  • 59
  • 36
  • 29
  • 28
  • 23
  • 19
  • 14
  • 14
  • 13
  • 9
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité

KO Validated
  • Épitope

    • 42
    • 24
    • 17
    • 14
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    IP/MS validation was supported by references (PMID:30377396)

     Réactivité croisée

    Humain, Souris, Rat, Mouton

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Calnexin. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2 , 293T Validation: Comparison, IP/MS, KO/KD, Orthogonal, Overexpression

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.46 mg/mL

    Buffer

    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Calnexin (CANX)

    Autre désignation

    calnexin

    Sujet

    Synonyms: calnexin , CNX , IP90 , P90

    Background: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

    Poids moléculaire

    68 kDa

    ID gène

    821

    UniProt

    P27824

    Pathways

    Signalisation MAPK, Thyroid Hormone Synthesis
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