Exportin 2 anticorps

N° du produit ABIN7468178

Cet anticorps anti-Exportin 2 est un anticorps Souris Monoclonal détectant Exportin 2 dans WB, IF et ICC. Adapté pour Humain.

Aperçu rapide pour Exportin 2 anticorps (ABIN7468178)

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Exportin 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: KO Validated

Clone: GT5111

Détail du produit anti-Exportin 2 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Affinity purified by Protein G.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.

Isotype: IgG2b

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2 , 293T Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Exportin 2

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Autre désignation: chromosome segregation 1 like

Sujet:

Synonyms: chromosome segregation 1 like , CAS , CSE1 , XPO2

Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]

Poids moléculaire: 110 kDa

ID gène: 1434

UniProt: P55060

Pathways: Protein targeting to Nucleus