TNNT1 anticorps

N° du produit ABIN7468979

Cet anticorps anti-TNNT1 est un anticorps Lapin Polyclonal détectant TNNT1 dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour TNNT1 anticorps (ABIN7468979)

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TNNT1 anticorps

Réactivité croisée: Humain, Porc

Purification: Purified by antigen-affinity chromatography.

Immunogène: Full length human Troponin T1 (slow) skeletal muscle Recombinant protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.89 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TNNT1

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Autre désignation: troponin T1, slow skeletal type

Sujet:

Synonyms: troponin T1, slow skeletal type , ANM , NEM5 , STNT , TNT , TNTS

Background: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Poids moléculaire: 33 kDa

ID gène: 7138

UniProt: P13805