TSG101 anticorps (AA 167-374)

N° du produit ABIN7469107

L’anticorps Souris Monoclonal anti-TSG101 a été validé pour WB, IHC, ELISA, IF, IP, FACS, IHC (p), ICC, IEM et IHC (ff). Il convient pour détecter TSG101 dans des échantillons de Humain.

Aperçu rapide pour TSG101 anticorps (AA 167-374) (ABIN7469107)

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM), Immunohistochemistry (Free Floating) (IHC (ff))

Classe de qualité: KO Validated

Clone: 4A10

Détail du produit anti-TSG101 anticorps

Épitope: AA 167-374

Specificité: Knockdown/Knockout validation was supported by references (PMID:27226592)

Réactivité croisée: Chien, Hamster, Humain, Singe, Souris, Porc, Rat, Poisson zèbre (Danio rerio)

Purification: Purified by antigen-affinity chromatography.

Immunogène: Amino acids 167-374 of TSG101 protein expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:500-1:1000. IHC-P: 1:100-1:1000. FACS: 1:25-1:200. EM: 1:10. IHC: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , K562 , THP-1 , HL-60 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , NIH-3T3 , JC , BCL-1 Validation: KO/KD, Orthogonal, Overexpression, Recombinant antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.8 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: tumor susceptibility 101

Sujet:

Synonyms: tumor susceptibility 101 , TSG10 , VPS23

Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

Poids moléculaire: 44 kDa

ID gène: 7251

UniProt: Q99816