ULK1 anticorps (pSer758)

N° du produit ABIN7469130

Cet anticorps Lapin Polyclonal détecte spécifiquement ULK1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour ULK1 anticorps (pSer758) (ABIN7469130)

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ULK1 anticorps

Épitope: pSer758

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide surrounding phospho Ser758 of human ULK1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: MCF-7 ( starvation for 16 hr incubated in EBSS for 4 hr and 200 nM Rapamycin treatment for 0.5 hr) Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ULK1

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Autre désignation: unc-51 like autophagy activating kinase 1

Sujet:

Synonyms: unc-51 like autophagy activating kinase 1 , ATG1 , ATG1A , UNC51 , Unc51.1 , hATG1

Background: Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells.

Poids moléculaire: 113 kDa

ID gène: 8408

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy