FANCD2 anticorps

N° du produit ABIN7469359

L’anticorps Souris Monoclonal anti-FANCD2 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter FANCD2 dans des échantillons de Humain.

Aperçu rapide pour FANCD2 anticorps (ABIN7469359)

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FANCD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: KO Validated

Clone: 103

Détail du produit anti-FANCD2 anticorps

Réactivité croisée: Humain

Purification: Protein G purified

Immunogène: Human FANCD2 fusion protein

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , HeLa Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur FANCD2

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Autre désignation: FANCD2

Sujet:

Synonyms: FA complementation group D2 , FA-D2 , FA4 , FACD , FAD , FAD2 , FANCD

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Poids moléculaire: 164 kDa

ID gène: 2177

UniProt: Q9BXW9

Pathways: Réparation de l'ADN