ADAM10 anticorps

N° du produit ABIN7505861

Cet anticorps anti-ADAM10 Monoclonal Souris (Clone 11G2) (ABIN7505861) détecte spécifiquement ADAM10 dans WB, FACS, IP, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ADAM10 anticorps (ABIN7505861)

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADAM10 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 11G2

Détail du produit anti-ADAM10 anticorps

Fonction: Anti-Hu CD156c Purified

Aucune reactivité croisée: Souris

Attributs du produit: The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.

Purification: Purified by protein-A affinity chromatography.

Immunogène: Jurkat cells

Isotype: IgG1, kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-5 μg/mL, extracellular and intracellular staining.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur ADAM10

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Autre désignation: CD156c

Sujet: ADAM metallopeptidase domain 10,CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.,ADAM10, AD10, RAK, MADM, HsT18717

ID gène: 102

UniProt: O14672

Pathways: Signalisation Notch, EGFR Signaling Pathway