Cet anticorps Rat Monoclonal détecte spécifiquement Galectin 3 dans WB, ICC, IP, IHC (p), FACS et ICFC. Il présente une réactivité avec des échantillons de Humain et Souris.
The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.
LGALS3
Reactivité: Humain, Souris
ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Flow cytometry: Recommended dilution: 2-6 μg/mL. Extracellular and intracellular staining.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Antigène
Galectin 3 (LGALS3)
Autre désignation
Galectin-3
Sujet
Lectin, galactose binding, soluble 3,Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.,Mac-2, GBP, Gal-3, L-34