HLA-C anticorps

N° du produit ABIN7505980

L’anticorps anti-HLA-C Monoclonal Souris est utilisé pour la détection de HLA-C dans des échantillons de Humain et Non-Human Primate. Il a été validé pour IP et FACS.

Aperçu rapide pour HLA-C anticorps (ABIN7505980)

Antigène: HLA-C (Major Histocompatibility Complex Class I C (HLA-C))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-C est non-conjugé

Application: Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: DT-9

Détail du produit anti-HLA-C anticorps

Fonction: Anti-HLA-C Purified

Attributs du produit: The mouse monoclonal antibody DT-9 recognizes an extracellular epitope on HLA-C member of MHC class I molecules. It does not crossreact with HLA-A or HLA-B allotypes.

Purification: Purified by protein-A affinity chromatography.

Immunogène: Purified MHC class I molecules of tamarin origin

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur HLA-C

Antigène: HLA-C (Major Histocompatibility Complex Class I C (HLA-C))

Autre désignation: HLA-C

Sujet: Major histocompatibility complex, class I, C,HLA-C, a member of MHC class I glycoproteins, is one of polymorphysm typing targets, which are important for transplantation. The HLA system plays an important role in the occurrence and outcome of infectious diseases. The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions. Individual HLA genetic variation may help explain different immune responses to a virus across a population. It has been described that HLA-C interacts with human herpesvirus 8 MIR1 protein.,HLC-C, D6S204, PSORS1, HLA-JY3

ID gène: 3107

UniProt: P10321

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response