SIGLEC8 anticorps (Extracellular Domain) (PE)

N° du produit ABIN7506011

Cet anticorps anti-SIGLEC8 est un anticorps Souris Monoclonal détectant SIGLEC8 dans FACS. Adapté pour Humain.

Aperçu rapide pour SIGLEC8 anticorps (Extracellular Domain) (PE) (ABIN7506011)

Antigène: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC8 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 7C9

Détail du produit anti-SIGLEC8 anticorps (PE)

Épitope: Extracellular Domain

Fonction: Anti-Hu SIGLEC8 PE

Specificité: The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur SIGLEC8

Antigène: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Autre désignation: SIGLEC8

Sujet: Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2

ID gène: 27181

UniProt: Q9NYZ4