TOMM34 anticorps

N° du produit ABIN7506025

L’anticorps Souris Monoclonal anti-TOMM34 a été validé pour WB, IP et ICC. Il convient pour détecter TOMM34 dans des échantillons de Humain.

Aperçu rapide pour TOMM34 anticorps (ABIN7506025)

Antigène: TOMM34 (Translocase of Outer Mitochondrial Membrane 34 (TOMM34))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TOMM34 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: Tomm34-4-1

Détail du produit anti-TOMM34 anticorps

Fonction: Anti-Hu Tomm34 Purified

Specificité: The mouse monoclonal antibody Tomm34-4.1 recognizes an epitope within TPR2 domain of human Tomm34 protein.

Purification: Purified by protein-A affinity chromatography.

Immunogène: Recombinant human Tomm34

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur TOMM34

Antigène: TOMM34 (Translocase of Outer Mitochondrial Membrane 34 (TOMM34))

Autre désignation: Tomm34

Sujet: Translocase of outer mitochondrial membrane 34,Tomm34 (translocase of the outer mitochondrial membrane 34) is an additional component of the cellular chaperone system involved in protein folding. As the name suggests, Tomm34 was initially identified as being involved in mitochondrial protein processing. Subsequent studies have shown that Tomm34 interacts with both Hsp70 and Hsp90 and modifies their protein folding activities. In cancer, high levels of Tomm34 have been reported in bladder, colorectal and breast cancers compared to their normal tissue counterparts. In these cancers, Tomm34 promotes colorectal cancer cell growth and is a biomarker of poor outcome in early invasive breast cancer and bladder cancer. As a tumour-associated protein, Tomm34 peptide vaccination is under investigation as a therapeutic option for colorectal cancer, with significant Tomm34 cytotoxic T-lymphocyte (CTL) response observed.,URCC3, HTOM34P

ID gène: 10953

UniProt: Q15785