RNF43 anticorps (AA 41-140)

N° du produit ABIN721600

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF43 dans ELISA, WB, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour RNF43 anticorps (AA 41-140) (ABIN721600)

Antigène: RNF43 (Ring Finger Protein 43 (RNF43))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF43 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RNF43 anticorps

Épitope: AA 41-140

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RNF43

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RNF43

Antigène: RNF43 (Ring Finger Protein 43 (RNF43))

Autre désignation: RNF43

Sujet:

Synonyms: URCC, RNF124, E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RNF43

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

ID gène: 54894

UniProt: Q68DV7

Pathways: Signalisation WNT