ITGA4 anticorps (PE-Cy7)

N° du produit ABIN7536955

Cet anticorps anti-ITGA4 est un anticorps Souris Monoclonal détectant ITGA4 dans FACS. Adapté pour Humain.

Aperçu rapide pour ITGA4 anticorps (PE-Cy7) (ABIN7536955)

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA4 est conjugé à/à la PE-Cy7

Application: Flow Cytometry (FACS)

Clone: HP1-2

Détail du produit anti-ITGA4 anticorps (PE-Cy7)

Fonction: PE/Cyanine7 Anti-Human CD49d Antibody [HP1/2]

Purification: Purified

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: (ABIN7469781)

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: CD49d

Sujet: CD49d,VLA-4 α chain, α4 integrin, Integrin α4 chain, ITGA4,CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

ID gène: 3676

UniProt: P13612

Pathways: Integrin Complex