EPH Receptor A3 anticorps (AA 401-500) (FITC)

N° du produit ABIN721982

L’anticorps Lapin Polyclonal anti-EPH Receptor A3 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter EPH Receptor A3 dans des échantillons de Souris et Rat.

Aperçu rapide pour EPH Receptor A3 anticorps (AA 401-500) (FITC) (ABIN721982)

Antigène: EPH Receptor A3 (EPHA3)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A3 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-EPH Receptor A3 anticorps (FITC)

Épitope: AA 401-500

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Eph receptor A3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EPH Receptor A3

Antigène: EPH Receptor A3 (EPHA3)

Autre désignation: Eph receptor A3

Sujet:

Synonyms: EK4, ETK, HEK, ETK1, HEK4, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, Human embryo kinase, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, Eph-like tyrosine kinase 1, EPHA3

Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

ID gène: 2042

UniProt: P29320

Pathways: Signalisation RTK, Regulation of Cell Size