CTLA4 anticorps

N° du produit ABIN7539448

Cet anticorps Souris Monoclonal détecte spécifiquement CTLA4 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CTLA4 anticorps (ABIN7539448)

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTLA4 est non-conjugé

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: A3-4H2

Détail du produit anti-CTLA4 anticorps

Fonction: CD152 Unconjugated Antibody

Attributs du produit: The clone A3.4H2, a mouse monoclonal antibody, selectively binds to the human 33- kDa member of the immunoglobulin superfamily, also known as Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CD152 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. Intracellular CD152 is also expressed on regulatory T cells and contributes to their inhibitory function.

Purification: Purified

Pureté: >95 %

Immunogène: Activated T cells

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CTLA4

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Autre désignation: CD152

ID gène: 2214

UniProt: Q92835

Pathways: Cancer Immune Checkpoints