CTLA4 anticorps (iFluor™488)

N° du produit ABIN7539512

L’anticorps anti-CTLA4 Monoclonal Souris est utilisé pour la détection de CTLA4 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour CTLA4 anticorps (iFluor™488) (ABIN7539512)

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTLA4 est conjugé à/à la iFluor™488

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade (Analyte)

Clone: A3-4H2

Détail du produit anti-CTLA4 anticorps (iFluor™488)

Fonction: CD152 iFluor488 Antibody

Attributs du produit: The clone A3.4H2, a mouse monoclonal antibody, selectively binds to the human 33- kDa member of the immunoglobulin superfamily, also known as Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CD152 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. Intracellular CD152 is also expressed on regulatory T cells and contributes to their inhibitory function.

Purification: Purified

Pureté: >95 %

Immunogène: Activated T cells

Isotype: IgG2a, kappa

Information d'application

Indications d'application: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C, Conjugated antibodies should never be frozen.

Détails sur CTLA4

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Autre désignation: CD152

ID gène: 929

UniProt: P08571

Pathways: Cancer Immune Checkpoints