CD40 Ligand anticorps
Aperçu rapide pour CD40 Ligand anticorps (ABIN7539620)
Antigène
Voir toutes CD40 Ligand (CD40LG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- AF/LE Purified Anti-Human CD154 Antibody [24-31]
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Specificité
- Human
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Purification
- Protein A/G Purified
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niveau d'endotoxine
- Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.
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Immunogène
- Recombinant Human CD154 protein
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Isotype
- IgG1, kappa
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Indications d'application
- FCM:2 μg/mL(1x10^5-5x10^5 cells)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- ≥ 1 mg/mL
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Buffer
- Sterile PBS.
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- CD40 Ligand (CD40LG)
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Autre désignation
- CD154
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Sujet
- CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
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ID gène
- 959
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UniProt
- P29965
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Pathways
- Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Antigène
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