CCR7 anticorps

N° du produit ABIN7539624

Cet anticorps Souris Monoclonal détecte spécifiquement CCR7 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CCR7 anticorps (ABIN7539624)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR7 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: G043H7

Détail du produit anti-CCR7 anticorps

Fonction: AF/LE Purified Anti-Human CD197 Antibody [G043H7]

Specificité: Human

Purification: Protein A/G Purified

niveau d'endotoxine: Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.

Immunogène: Recombinant Human CD197 protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: FCM:2 μg/mL(1x10^5-5x10^5 cells)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS.

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CD197

Sujet: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

ID gène: 1236

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process