Endothelin 1 anticorps (AA 18-212)

N° du produit ABIN7539670

L’anticorps Souris Monoclonal anti-Endothelin 1 a été validé pour ELISA, ICC et FACS. Il convient pour détecter Endothelin 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Endothelin 1 anticorps (AA 18-212) (ABIN7539670)

Antigène: Endothelin 1 (EDN1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Endothelin 1 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 4E6E5

Détail du produit anti-Endothelin 1 anticorps

Épitope: AA 18-212

Fonction: EDN1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Endothelin 1

Antigène: Endothelin 1 (EDN1)

Autre désignation: EDN1

Sujet: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 24.4 kDa

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size