SELPLG anticorps (AA 42-320)
Aperçu rapide pour SELPLG anticorps (AA 42-320) (ABIN7539682)
Antigène
Voir toutes SELPLG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 42-320
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Fonction
- CD162 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CD162 (AA: 42-320) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SELPLG (Selectin P Ligand (SELPLG))
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Autre désignation
- CD162
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Sujet
- This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
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Poids moléculaire
- 43.2 kDa
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UniProt
- Q14242
Antigène
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