NOTCH2 anticorps (AA 1391-1677)

N° du produit ABIN7539764

Cet anticorps anti-NOTCH2 est un anticorps Souris Monoclonal détectant NOTCH2 dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour NOTCH2 anticorps (AA 1391-1677) (ABIN7539764)

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOTCH2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 4C5A8

Détail du produit anti-NOTCH2 anticorps

Épitope: AA 1391-1677

Fonction: NOTCH2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human NOTCH2 (AA:1391-1677) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur NOTCH2

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Autre désignation: NOTCH2

Sujet: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 265.4 kDa

ID gène: 4853

Pathways: Signalisation Notch, Stem Cell Maintenance