TCF7 anticorps (AA 168-358)

N° du produit ABIN7539769

L’anticorps Souris Monoclonal anti-TCF7 a été validé pour ELISA, IHC, ICC et FACS. Il convient pour détecter TCF7 dans des échantillons de Humain.

Aperçu rapide pour TCF7 anticorps (AA 168-358) (ABIN7539769)

Antigène: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCF7 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 1B4E9

Détail du produit anti-TCF7 anticorps

Épitope: AA 168-358

Fonction: TCF7 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TCF7 (AA: 168-358) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TCF7

Antigène: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Autre désignation: TCF7

Sujet: This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.

Poids moléculaire: 41.6 kDa

ID gène: 6932

UniProt: P36402

Pathways: Signalisation WNT